Mewtwo is one of the most powerful and iconic Pokemon ever created. Born from genetic experiments on Mew, it starred in the very first Pokemon movie and has been a fan favourite ever since. Every new Mewtwo Pokemon card attracts attention, and some older ones are among the most loved cards of the vintage era.
This guide covers nine famous Mewtwo cards, explains why Mewtwo is so collectable and shares tips for building a Mewtwo collection.
Why Collect a Mewtwo Pokemon Card?
Mewtwo is number 150 in the National Pokedex and one of the original Legendary Pokemon from Kanto. Its dramatic story, powerful design and role in Pokemon: The First Movie made it a superstar. A Mewtwo Pokemon card has been printed in almost every era of the game, so there are cards for every budget.
9 Best Mewtwo Cards
1. Base Set Mewtwo holo
The original 1999 Mewtwo holo from Base Set is a nostalgic classic. First edition and shadowless copies are especially valuable.
2. Movie promo Mewtwo
Promo cards released alongside Pokemon: The First Movie introduced many fans to the hobby. They remain popular with vintage collectors.
3. Shining Mewtwo
The Shining Mewtwo from Neo Destiny is one of the most desirable vintage cards, with its striking shiny colours.
4. Mewtwo ex from the EX era
The EX series introduced powerful Mewtwo ex cards that are now favourites with collectors of the early 2000s.
5. Mewtwo GX
Mewtwo GX cards from the Sun and Moon era, including full art versions, are popular modern collectables.
6. Mewtwo and Mew GX alternate art
The Tag Team Mewtwo and Mew GX alternate art from Unified Minds is one of the most famous cards of its era.
7. Mewtwo VSTAR
The Pokemon GO special set included Mewtwo V and Mewtwo VSTAR, including stunning rainbow and gold versions.
8. Team Rocket’s Mewtwo ex Special Illustration Rare
Destined Rivals introduced Team Rocket’s Mewtwo ex, and its Special Illustration Rare, number 231/182, is one of the biggest chase cards of the set. Our Destined Rivals booster bundle guide covers the set.
9. Japanese Mewtwo promos
Japan has released many Mewtwo promos for movies, events and Pokemon Center campaigns. They are a great way to add unique artwork to a collection.
What Is a Mewtwo Pokemon Card Worth?
Values vary widely. Modern regular Mewtwo cards are usually affordable, while vintage holos, Shining Mewtwo and modern Special Illustration Rares can be worth much more. As with any card, value depends on rarity, condition and demand.
How to check a value
- Find the set symbol and collector number.
- Check the rarity and version.
- Assess the condition carefully.
- Compare recent sold prices for the exact card.
Our Pokemon card value guide explains each step.
How to Build a Mewtwo Collection
- Choose a scope. Every Mewtwo card ever, one era or just special rarities.
- Start affordable. Regular modern Mewtwo cards are cheap and fun.
- Add one premium card at a time. Save for a vintage holo or modern chase card.
- Include Mew. Mew and Mewtwo look great together in a binder.
- Protect every card. Sleeves and toploaders keep cards in great condition.
A Vivid 9 pocket zip binder holds up to 360 sleeved cards, enough for a big Mewtwo collection.
Mewtwo Through the Eras
Every era of the game has given collectors a different kind of Mewtwo Pokemon card.
The Wizards of the Coast era
From 1999 to 2003, Mewtwo appeared in Base Set, promos and later sets. These cards have simple, classic artwork and a strong nostalgic pull for fans who grew up with the original games.
The EX and Diamond and Pearl eras
These eras introduced powerful Pokemon ex and Pokemon LV.X cards, along with new artwork styles. Mewtwo cards from this period are popular with collectors who love early 2000s design.
The Sun and Moon and Sword and Shield eras
GX, V, VMAX and VSTAR cards brought full arts, rainbow rares and alternate arts. This was a golden age for spectacular Mewtwo artwork.
The Scarlet and Violet and Mega Evolution eras
The newest Mewtwo Pokemon card designs are some of the most detailed ever. Modern sets feature Illustration Rares and Special Illustration Rares, which show Pokemon in detailed scenes. Team Rocket’s Mewtwo ex brought Mewtwo back as a headline chase card.
Mewtwo in Pokemon Movies
Many fans bought their first Mewtwo Pokemon card because of the movies. Mewtwo’s role in Pokemon: The First Movie made it a household name. The film was later remade as Mewtwo Strikes Back Evolution. Movie tie-ins have produced special Mewtwo promos in several countries, which are great additions to any collection.
Mewtwo in the Trading Card Game
Mewtwo has often been a strong Psychic attacker. Many versions have high damage attacks or useful Abilities. If you want to play a Mewtwo deck, check which cards are legal in the current Standard format on the official Play! Pokemon website.
Mewtwo and Mew
Mewtwo’s story is linked to Mew, the Mythical Pokemon it was created from. Many collectors build binders featuring both. Our Pokemon Mew cards guide covers the best Mew cards.
Spotting Fake Mewtwo Cards
Popular cards are often faked. Check the font, colours, holo pattern and card back. Compare with a genuine card and buy from trusted sellers. Our guide on how to tell if Pokemon cards are fake explains the checks.
Grading a Mewtwo Pokemon Card
If you have a vintage Mewtwo holo or a modern Special Illustration Rare in great condition, grading can protect it and add value. Check centring, corners, edges and surface before you submit. Our graded Pokemon cards guide explains how grading works.
Displaying Your Mewtwo Collection
Purple Psychic cards look great on black binder pages. For a favourite card, use a magnetic holder on a shelf away from direct sunlight. Our premium card sleeves keep cards protected before they go on display.
Mewtwo Pokemon Card FAQ
What is the best Mewtwo Pokemon card?
It depends on your taste. Base Set Mewtwo, Shining Mewtwo and Team Rocket’s Mewtwo ex SIR are three of the most popular.
What number is Mewtwo in the Pokedex?
Mewtwo is number 150.
Which set has Team Rocket’s Mewtwo ex?
Destined Rivals, released on 30 May 2025.
Where can I see every Mewtwo card?
The official Pokemon card database lists every official Mewtwo card.
Every Mewtwo Pokemon card carries a little of the legend that made Mewtwo famous. Start with a few favourites, protect them well and build a collection worthy of the Genetic Pokemon.
